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As with the response catalyzed by FBPase-1, this is an irreversible reaction. The ΔG°′ -13.8 kJ/mol (-3.Three kcal/mol). To prevent interference with glycolysis, which occurs within the cytosol, the glucose 6-phosphatase activity is spatially restricted to the endoplasmic reticulum lumen, guaranteeing compartmental separation of opposing pathways. Glucose and inorganic phosphate are exported from the endoplasmic reticulum to the cytosol by distinct transporters, probably T2, for glucose, and T3, an anion transporter for inorganic phosphate. Finally, glucose leaves the hepatocyte via the GLUT2 transporter, enters the bloodstream, and is delivered to tissues in want.<br><br>Darras, B. T.; Friedman, N. R. (February 2000). "Metabolic myopathies: a clinical approach; half I". Bhavaraju-Sanka, R.; Jackson, C. E. (2014-01-01), "Myopathy, Endocrine", [https://systemcheck-wiki.de/index.php?title=Benutzer:SallyDuvall48 Healthy Flow Blood benefits] in Aminoff, Michael J.; Daroff, Robert B. 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Celsing, F.; Blomstrand, E.; Melichna, J.; Terrados, N.; Clausen, N.; Lins, P. E.; Jansson, E. (April 1986). "Effect of hyperthyroidism on fibre-sort composition, fibre space, glycogen content and enzyme activity in human skeletal muscle".<br>

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