JLAB12 is an INFN experiment in the CSNIII that includes all Italian activities at Thomas Jefferson National Accelerator Facility (USA). Jefferson Lab is a mid-size US-DOE national laboratory for nuclear physics hosting CEBAF (Continuous Electron Beam Accelerator Facility), a medium energy (~10 GeV) electron accelerator, and four experimental halls, A to D, equipped with advanced particle detectors. The goal of the experiment is the study of the structure and dynamics of hadrons and nuclei through the scattering of (longitudinally polarized) ~10 GeV electrons on (polarized) fixed nuclear targets. More than 50 Italian physicists and engineers collaborate with the 1300 researchers of the JLab community to run experiments and carry out a broad program in hadronic physics. The JLAB12 main research areas are: nucleon and nuclei form factors; nucleon structure functions; electromagnetic and weak electron-hadron interactions; meson spectroscopy; hadron interactions in (hyper)nuclei; Physics beyond the Standard Model. JLAB12 experimental activity is supported by the Italian theoretical physics community that participates with more than 30 researchers in the study of QCD (Quantum Chromo Dynamics), that governs the structure of hadrons, and to the interpretation of experimental results.